Before breaking point, there's CareLoop Health

At CareLoop Health, we're transforming care for people living with severe mental illnesses through our breakthrough platform that integrates P4 medicine: Predictive, Preventative, Personalised, and Participatory.

Our vision

We envision a world where predictive, personalised care keeps people with severe mental illness well at home and connected to their communities, preventing escalation and eliminating crisis.

Our mission

We're on a mission to transform mental healthcare using intelligent software to predict problems, prevent escalation, and personalise care to individual needs while supporting patient participation.

As healthcare systems struggle to meet increasing demand, both human and financial costs rise. Our approach shifts care from reactive to proactive, helping more people stay well in their communities.

CareLoop team and product

The challenge

5% of the global population has a severe mental health problem, with many experiencing crisis episodes requiring acute care. For those with psychosis:

  • Only 20% achieve full recovery
  • The remaining 80% face a 25% annual relapse risk
  • Early warning signs appear just 3–10 days before relapse
  • Traditional care models often schedule appointments 12 weeks apart

This gap leads to preventable crises with devastating human costs — reduced life expectancy, 93% unemployment rate — and financial burden, consuming 4% of the NHS budget in the UK and $62 billion annually in the US.

Our approach

CareLoop integrates P4 medicine to enhance outcomes for people with severe mental illness:

  • Predictive: Our system detects early warning signs before relapse.
  • Preventative: We identify subtle changes to reduce hospital admissions.
  • Personalised: Each care pathway is tailored to individual needs.
  • Participatory: We empower patients to actively engage in their care.

Our platform has been co-designed at every stage by the people who matter most:

  • Individuals: lived experience and practical insights
  • Clinicians: alignment with clinical best practice
  • Researchers: evidence-based methodologies
  • Software engineers: intuitive, effective technology

As a spinout of the University of Manchester, we maintain strong links with our academic heritage and relationships within the NHS.

As a business and as individuals, we recognise our responsibility to protect the planet for future generations. To achieve Net Zero carbon emissions by 2045, we are mindful of how we work and who we partner with.

The team

Zoë Blake

Zoë Blake

Chief Executive Officer & Co-Founder

Zoë is our Chief Executive Officer. Before joining CareLoop Health she served as CEO of the digital mental health platform Kooth (previously XenZone). She has over 25 years leading teams in fast-changing, innovation-led organisations.

Pauline Whelan

Pauline Whelan

Chief Operating Officer & Co-Founder

In her 20+ years in software engineering, Pauline has led teams in consultancies, corporates and academia. She has built digital health solutions deployed in the NHS, and is a Digital Health Lead at the University of Manchester and Digital Director of GM.Digital at Greater Manchester Mental Health NHS Foundation Trust.

Prof. Sandra Bucci

Prof. Sandra Bucci

Chief Clinical Officer & Co-Founder

Sandra is the first NIHR Research Professor in Digital Mental Health in the UK, Professor of Clinical Psychology at The University of Manchester, and Honorary Consultant Clinical Psychologist at Greater Manchester Mental Health NHS Foundation Trust. She is also co-Director of the Complex Trauma and Resilience Research Unit.

Prof. Shôn Lewis

Prof. Shôn Lewis

Chief Medical Officer & Co-Founder

A psychiatrist for over 30 years, Shôn’s interest in digital technology within mental health was the genesis of CareLoop Health. He trained at the Maudsley Hospital and has worked within the NHS throughout his career, including a platinum clinical excellence award for contribution to the NHS.

Prof. John Ainsworth

Prof. John Ainsworth

Director & Co-Founder

John is Chief Product Officer at CareLoop Health. Professor of Health Informatics at the University of Manchester and former Director of the Centre for Health Informatics, he has undertaken pioneering research into smartphones in mental health for connected care since 2009.